Single cell analysis is the study of various molecular aspects of individual cells, such as their DNA, RNA, proteins, and metabolites. It is a powerful approach to understand the diversity and function of cells in complex biological systems, such as tissues, organs, and organisms. Single cell analysis can reveal the heterogeneity of cell populations, the […]
Single Cell Analysis Techniques: What, Why and How Read More »
Next-generation sequencing (NGS) is a revolutionary technology that has enabled the rapid and high-throughput generation of massive amounts of genomic data. NGS has transformed the fields of biology, medicine, and biotechnology by providing unprecedented insights into the structure, function, and evolution of genomes. However, NGS also poses significant challenges for data analysis, as the raw
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Bioinformatics is a rapidly evolving field that deals with the analysis and interpretation of large and complex biological data sets. Bioinformatics applications range from genome sequencing and annotation, to protein structure prediction and drug discovery, to systems biology and personalized medicine. However, bioinformatics also faces many challenges, such as: The increasing volume, variety, and velocity
Cloud computing in Bioinformatics: A game-changer for big data analysis Read More »
Metabolomics is the study of small molecules (metabolites) that are involved in the biochemical processes of living organisms. Metabolites are the end products of gene expression and can reflect the physiological state of a cell or a tissue under different conditions. Metabolomics can provide insights into the molecular mechanisms of health and disease, as well
Sequence and structure databases are essential resources for bioinformatics, as they store and provide access to the vast amount of biological data generated by various experimental methods. Sequence databases contain the information of nucleic acids (DNA and RNA) and proteins, while structure databases store the three-dimensional coordinates of macromolecules and their complexes. In this blog,
Dive into the intricate realm of single-cell RNA sequencing (scRNA-Seq) for profound insights into cellular processes. This blog delves into the basics, methodology, and applications of scRNA-Seq, enriched by recent research findings. Refining Data: Preprocessing and Noise Control Start with tools like Cutadapt and Trimmomatic to eliminate adapter sequences and enhance data quality. SinQC identifies
Wonders of Cellular Complexity through Single-Cell RNA Sequencing (scRNA-Seq) Read More »
Next-Gen Sequencing (NGS) is a powerful technique that can reveal the secrets of the genome, transcriptome, epigenome, and metagenome of any organism. NGS has many applications in biomedical research, clinical diagnostics, agriculture, forensics, and environmental studies. Learning NGS can boost your career prospects and open new opportunities in the field of genomics and bioinformatics. NGS
The Future Scope of Next Generation Sequencing (NGS) Read More »
Virtual screening is a computational technique used in drug discovery to identify potential molecules with desired properties from large databases. Through simulations and predictive modeling, virtual screening evaluates the interactions between molecules and target proteins, predicting their binding affinities and potential biological activities. This approach accelerates the identification of promising candidates, streamlining the initial stages
An introduction to Virtual Screening Read More »
Small molecule drugs are compounds that can modulate the activity of biological targets, such as proteins, enzymes, or receptors, and have the potential to treat various diseases. These are the most common type of therapeutics, accounting for about 90% of the approved drugs on the market. However, discovering and developing new small molecule drugs is
How Machine Learning Can Accelerate Small Molecule Drug Discovery Read More »
Bioinformatics is the application of computational methods to analyze biological data, such as DNA, RNA, proteins, and metabolites. Bioinformatics has become an essential tool for advancing our understanding of life sciences, as well as for developing new diagnostics, therapeutics, and biotechnology products. In this blog, we will explore some of the current trends and developments
Current Challenges in Bioinformatics Research Read More »
