Health Genomics

Supercoiling in Eukaryotes vs. Prokaryotes

Supercoiling in Eukaryotes vs. Prokaryotes – Twisting Tails: A Tale of Two Genomes

DNA packaging in prokaryotes is a distinct process from that in eukaryotes, as prokaryotic cells have a different organizational structure and lack a defined nucleus. This blog will delve into the unique aspects of DNA packaging in prokaryotes, highlighting the key differences between prokaryotic and eukaryotic cells. DNA Packaging in Prokaryotes In prokaryotic cells, DNA […]

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DNA Replication in Eukaryotes

DNA Replication in Eukaryotes: A Comprehensive Guide

DNA replication in eukaryotes is a complex and tightly regulated process that involves several enzymes and proteins. It is essential for the duplication of cells and the maintenance of the eukaryotic genome. This blog post will discuss the three main stages of eukaryotic DNA replication: initiation, elongation, and termination. Initiation During initiation, eukaryotic DNA is

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‘Omics’ based biomarkers for Cancer

Detecting biomarkers offers a solution to understand the complex pathogenesis of a disease. The major challenge lies in identifying unique molecular signatures in complicated biological mixtures which can unambiguously correlate to the biological events. A humongous amount of contribution comes from the high throughput ‘Omics’ technologies in biomarker discovery. Biomarkers stratify patient populations, quantify therapeutic

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Genomics News: Cognitive Test Scores, Brain Structures, and the Gut Microbiome in Children

The human gut microbiome is a complex ecosystem of microorganisms that play a crucial role in human health and development. Recent research has shown that the gut microbiome is linked to various aspects of human health, including cognitive development in children. Studies have found that the composition of the gut microbiome in infants and children

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FDA Approves First Oral High-Risk Neuroblastoma Maintenance Therapy

The U.S. Food and Drug Administration (FDA) has recently approved the first and only oral maintenance therapy, Iwilfin (eflornithine), to strengthen the fight against aggressive childhood cancer, specifically high-risk neuroblastoma. This approval marks a significant advancement in the treatment of this condition, providing a new and much-needed treatment option for both adult and paediatric patients.

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A Needle-Free Vaccine Patch: The Future of Zika Virus Protection

Imagine a world where protection against the Zika virus is as simple as applying a patch to your skin. Thanks to groundbreaking research, this future may not be far off. In a recent preclinical trial, a needle-free vaccine patch has shown promising results in safeguarding individuals from the potentially deadly mosquito-borne Zika virus. What is

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Role of Genetics in Cardiovascular Diseases

The Role of Genetics in Cardiovascular Diseases: Understanding Inherited Risks and Genetic Testing

The transfer of genes occurs from parents to children, along with inheriting the qualities of the parents, including the potential for diseases that may affect the children. One such disease is cardiovascular disease. Whenever the topic of genes is discussed, it is essential to understand that the inherited genes also come with potential risks. In

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