This test is ideal for individuals who:

• • Are on Cardiovascular Medications: This is tailored for those taking or considering statins, beta-blockers, ACE inhibitors, blood thinners, or other heart medications.
  • Have a History of Drug Side Effects: Designed for patients who have experienced adverse reactions, inefficacy, or challenges with current cardiovascular medications.
  • Are at Risk for Cardiovascular Disease: Beneficial for individuals with a family history of heart conditions or those seeking to manage potential genetic predispositions.
  • Require Complex Drug Regimens: Supports patients with multiple cardiovascular conditions, ensuring effective polypharmacy strategies.
  • Seek Personalized Treatment Plans: Offers tailored therapies for maximum efficacy and minimal side effects based on genetic insights.
  • Are Under Healthcare Supervision: Supports clinicians adopting heart genetic testing and precision medicine approaches for better patient outcomes.

Chronic illnesses are leading causes of death worldwide. Despite medical advancements, variability in drug response often leads to treatment failures or adverse drug reactions. These variations are influenced by genetic factors critical to drug metabolism and efficacy.

Key Benefits of the Test:

1. Avoid Incorrect Medications: Ensures appropriate prescriptions by leveraging genetic insights to prevent ineffective treatments.
2. Prevent Adverse Drug Reactions (ADRs): Identifies genetic variations that could trigger harmful reactions to medications like statins and blood thinners. (2)
3. Timely Treatment: Enables early detection of genetic risks, reducing the likelihood of severe cardiovascular events. (3)
4. Reduce Risk of Complications: Helps lower the chances of complications, such as stroke and arrhythmias.
5. Optimize Prevention: Facilitates targeted strategies to manage genetic predispositions, mitigating heart disease risks effectively. 

Common cardiovascular drugs, including anticoagulants, contribute to significant treatment costs, with adverse drug reactions (ADRs) accounting for 7.5–22.1% of anticoagulant-related ADRs and 7.0–36.0% for other cardiovascular drugs, leading to complications like bleeding and ICU stays. (1)

Statin-Related ADRs: Indians metabolize statins differently, which can affect drug levels and increase the risk of adverse effects. The SLCO1B1 gene variant is present in around 15% of Indians, leading to statin intolerance. (6)

Clopidogrel Resistance in Indian Patients: Clopidogrel resistance is observed in 15.4% (resistant) and 49.2% (semi-responders) of Indian patients, significantly affecting the drug’s efficacy in preventing cardiovascular events. (5)

Genetic Link to Resistance: The CYP2C19*2 polymorphism, a loss-of-function variant, is a major contributor to clopidogrel resistance, limiting its effectiveness. Identifying such genetic factors through PGx testing can guide alternative therapies for improved treatment outcomes. (5)

DrOmics Labs’ Comprehensive Cardio PGx Test combines advanced genetic analysis with personalized healthcare to optimize cardiovascular treatment. By evaluating your unique genetic profile, the test provides tailored recommendations on effective medications and dosages, minimizing the risk of adverse drug reactions and enhancing treatment safety and efficacy. Powered by cutting-edge technology, it delivers precise, reliable insights that guide informed decisions for improved heart health. This personalized approach not only ensures better treatment outcomes but also supports long-term cardiovascular well-being through a proactive, science-driven strategy.